Sedating allergy

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Sanofi-aventis also markets Allegra-D 12 Hour®, a formulation combined with an extended-release decongestant for effective and non-sedating relief of seasonal allergy symptoms including nasal congestion.In common use, the term "antihistamine" refers only to H In type I hypersensitivity allergic reactions, an allergen (a type of antigen) interacts with and cross-links surface Ig E antibodies on mast cells and basophils.Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil.Additionally, the increased fluid leakage from your blood vessels, combined with an increased mucous production — also caused by histamines — can result in a runny nose.Allergies occur when your immune system erroneously thinks an innocuous foreign substance, such as pollen or pet dander, is actually dangerous.

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